Effect of errors in charges: errors are immaterial unless they actually mislead the accused and cause failure of justice. Errors or omissions in stating an offence or particulars are not material unless the accused was actually misled and this caused a failure of justice. The provision emphasizes actual prejudice: if the accused nevertheless defends and adduces witnesses, inaccuracies may be immaterial; where uncertainty prevents the accused from knowing which transaction is charged or the trial proceeds on a different incident, the omission or error may be material.