<h1>Modernizing clinical research operations, regulatory harmonization, and capacity building to accelerate India's translational research and cross-border trials</h1> The symposium advanced three dominant policy prescriptions: endorsement of modernizing research operations and bolstering compliance-prescribing adoption of upgraded operational standards and enhanced regulatory compliance mechanisms, with the operative effect of facilitating more efficient and quality-assured clinical research conduct; advocacy for globally aligned regulatory and governance frameworks-prescribing harmonization of standards and ethical governance across jurisdictions, with the operative effect of enabling internationally accepted evidence generation and facilitating cross-border trials; and promotion of skill development, infrastructure and cross-sector collaboration-prescribing targeted capacity-building and public-private cooperation, with the operative effect of positioning India to accelerate translational research and integrate into global R&D pipelines.