Washington, Apr 4 (AP) After a long wait, the Senate is launching action on President Donald Trump's "big, beautiful bill” of tax breaks and spending cuts at a risky moment for the U.S. and global economy.

More than a month after House Republicans surprised Washington by advancing their framework for Trump's tax breaks and spending cuts package, Senate Republicans voted Thursday to start working on their version. The 52-48 vote sets the stage for back-to-back Senate all-nighters spilling into Friday and the weekend.

But work on the multitrillion-dollar package is coming as markets at home and abroad are on edge in the aftermath Trump's vast tariffs scheme, complicating an already difficult political and procedural undertaking.

Senate Majority Leader John Thune, R-S.D., opened the chamber Thursday saying they were expected to begin “as soon as today” embarking on what they hope will become the GOP's signature domestic policy package.

Trump says he's on board and Republicans, in control of Congress, are eager to show the party is making progress toward delivering on their campaign promises. After that, it's still long weeks, if not months, to go toward a final product.

Democrats, as the minority party, don't have the votes to stop the GOP plan. But they intend to use the procedural tools available to prolong the process. Democrats argue that Republicans are focusing on tax breaks for the wealthy at the expense of the programs and services millions of Americans rely on for help with health care, child care, school lunches and other everyday needs.

“They're mean, they're nasty, they're uncaring," Senate Democratic Leader Chuck Schumer said about the Republicans.

Senate Democrats are ready to spend the night and day ahead with floor debates over potential GOP cuts to Medicaid, veterans programs, DOGE cuts and the impact of Trump's tariffs. “We, tonight and tomorrow, are going to show just who they are,” Schumer said.

Fundamental to the Senate package is making sure Trump's first-term tax cuts, which are set to expire at the end of the year, are continued and made a permanent fixture of the tax code. The senators also will consider adding Trump's proposed tax cuts on tipped wages, Social Security income and others.

The Senate package also would bolster border security funds by some $175 billion to carry out Trump's mass deportation campaign, which is running short of cash, and it would add national security funds for the Pentagon — all priorities the Senate GOP tucked into an earlier version that was panned by House Republicans.

What's unclear is how it will all be paid for, since Republican deficit hawks typically require spending offsets to help defray the lost tax revenue and avoid piling onto the nation's USD 36 trillion debt load.

While House Republicans approved their package with USD 4.5 trillion in tax breaks and up to USD 2 trillion in spending cuts, the Senate Republicans are taking a different tack.

Senate Budget Committee Chairman Lindsey Graham is making the case that since the existing Trump tax breaks are the current policy, they are not considered new, and do not need to be offset with reductions in spending — an approach Democrats compare to “going nuclear” with the normal rules. Democrats are vowing to put the strategy to the test before the Senate parliamentarian.

Instead, Senate Republicans are considering offsets mostly for any new Trump tax breaks. Raising alarms from the most conservative budget hawks, the senators have set a floor of about USD 4 billion in budget reductions to health and other programs — a fraction of the package's expected USD 4 trillion-plus price tag for tax breaks.

GOP leaders are assuring the deficit hawks within their own ranks that the legislation says the cuts can rise to as much as USD 2 trillion.

After an expected Friday night vote-a-rama, with dozens of amendments being offered to the package, the senators are planning to stay into Saturday if needed to take a final vote to approve it, sending it to the House for action.

The House and Senate will ultimately need to merge their frameworks into a final product, expected in May, but House Speaker Mike Johnson's intention to have it all wrapped up by Memorial Day could prove optimistic.

The political environment is uncertain, and the public's appetite for steep budget cuts is being tested in real time, with Trump's Department of Government Efficiency headed by billionaire Elon Musk blazing through federal offices, firing thousands of workers and shuttering long-running government mainstays — from scientific research projects on diseases to educational services for schoolchildren to offices that help with Social Security, tax filing and the weather.

At the same time, the staunchest fiscal conservatives in both the House and Senate, many aligned with the Freedom Caucus, are pushing for even more cuts.

Trump told senators publicly and privately this week he would have their backs, particularly when it comes to standing up for the spending reductions. At a White House announcing the tariffs Wednesday, Trump said the Senate plan had his “complete and total support.” The president's steep tariffs threw the global economy into a tailspin Thursday, with stocks down around the world, the U.S. markets leading the way. (AP) ARD ARD

Tax permanence and offsets questioned as Republicans advance a package extending tax cuts amid spending-cut negotiations. Senate Republicans launched consideration of a package to extend and make permanent existing tax reductions and add new targeted tax cuts while proposing significant spending reallocations for border security and defense. Central procedural and fiscal tension surrounds whether continuing existing tax reductions requires spending offsets, with proponents treating current law as the baseline and opponents preparing parliamentary challenge. The measure anticipates targeted offsets for new tax provisions, potential cuts to domestic programs to satisfy fiscal conservatives, extended floor debate including a vote-a-rama, and eventual reconciliation with the House framework amid market and political uncertainty.