Prohibition on appointment of sole selling agents for specified drug categories, exempting Ayurvedic, Unani and Homoeopathic preparations. The Central Government prohibits the appointment of sole selling agents for every category of bulk drugs, drugs and formulations as defined in the Drugs (Prices Control) Order, 1995, when demand substantially exceeds production or supply and sole selling agent services are unnecessary to create a market, excluding bona fide Ayurvedic (including Siddha), Unani and Homoeopathic preparations; the prohibition operates for a prescribed period from the notification's Gazette publication and is grounded in the Government's statutory notification power.